Choriocapillary vascular density changes in choroidal neovascularization associated with choroidal nevus after anti-VEGF injections
- Resource Type
- Article
- Authors
- D’andrea, Luca; Fossataro, Federica; Cennamo, Gilda
- Source
- European Journal of Ophthalmology; March 2022, Vol. 32 Issue: 2 pNP114-NP117, 4p
- Subject
- Language
- ISSN
- 11206721; 17246016
Purpose: To evaluate choriocapillary vascular density changes in choroidal neovascularization (CNV) type 2 associated with choroidal nevus using optical coherence tomography angiography (OCT-A) before and after anti-VEGF treatment.Methods: Observational case report.Results: A 25-year-old woman, was referred to Eye Clinic and presented a decreased visual acuity in right eye. Fundus examination showed a pigmented lesion located in macular region associated with subretinal hemorrhages adjacent to the mass in right eye. The diagnosis of choroidal nevus-associated with CNV was made and confirmed by spectral domain (SD)-OCT, OCT-A, and ultrasound examination. Two monthly ranibizumab intravitreal injections (IVT) were performed and a regression of the activity of neovascular lesion was noted. OCT-A showed a reduction of choriocapillaris vessel density (VD) before the treatment and an increase of VD after IVT injections.Conclusion: OCT-A could be a non-invasive and diagnostic tool to evaluate choriocapillaris vascular changes after IVT injections in CNV associated with choroidal nevus.