Enterprise Service Bus (ESB) technology, which is one of the implementation of the infrastructure of Service-Oriented Architecture (SOA), is put forward to solve various heterogeneous problems in enterprise information sharing and the management system integration. First, this paper introduces the definition and technical features of ESB and then, shows the design and implementation of an ESB-based Manufacturing Business Collaboration Platform (MBCP), which is used to solve the problems of the business integration in manufacturing industry area. Finally, we presented the application of MBCP in a steel plant as an example to illustrate the effectiveness of MBCP.