Based on the theory of limit equilibrium, by the GEO-SLOPE software,analyzed the stability before and after reinforcement of a high Loess-bedrock slope. The results and conclusions show: (1)Analyzed and Optimized the high Loess-bedrock slope through SLOPE/W module, optimizing the engineering quantity of the anchor cable frame in the local and saving the investment; (2)When taken reinforcement measures, conducted the SLOPE/W model again, the stability coefficient is 1.459, the effect testified by projects is obvious; (3)Aiming at the optimization analysis, proposed countermeasures system, with reference for reinforcement of a high Loess-bedrock slope.