Fast-atom bombardment-induced condensation of glycerol with ammonium surfactants II: Time dependence of mass spectra and tandem mass spectra
- Resource Type
- Article
- Authors
- Tuinman, Albert A.; Cook, Kelsey D.
- Source
- Journal of the American Society for Mass Spectrometry; February 1994, Vol. 5 Issue: 2 p92-99, 8p
- Subject
- Language
- ISSN
- 10440305; 18791123
Studies of fast-atom bombardment (FAB)-induced condensation between trimethyltetradecylammonium cations and glycerol have been extended to consider spectral time dependence. To enhance reproducibility of time dependence, a modified FAB target was used. FAB mass spectrometry of deuterium-labeled surfactants and FAB/collision-induced dissociation (CID) of nonlabeled material demonstrate that products of condensation at the surfactant “head group” predominate early in the analysis, while tail adducts become prominent later. This time dependence correlates with the expected surface activity of the products. It is incompatible with gas-phase reaction, but consistent with reaction in the condensed phase. Subtle variations in the surface activities of various condensation products (derived from changes in the number of hydroxyls from the reactive glycerol radical or in the position of attack along the surfactant chain) are reflected in the time dependence of FAB and CID spectra. CID spectra of deuterium-labeled cations provide evidence for intramolecular hydrogen transfer from the surfactant tail to the head within a surfactant radical. This transfer shows no significant kinetic isotope effect.