Effects of the CYP3A53variant on cyclosporine exposure and acute rejection rate in renal transplant patients a meta-analysis
- Resource Type
- Article
- Authors
- Tang, Hui-Lin; Ma, Lu-Lin; Xie, Hong-Guang; Zhang, Ting; Hu, Yong-Fang
- Source
- Pharmacogenetics and Genomics; September 2010, Vol. 20 Issue: 9 p525-531, 7p
- Subject
- Language
- ISSN
- 17446872; 17446880
Whether the loss-of-function allele CYP3A53variant is associated with significantly impaired metabolism of cyclosporine A (CsA) in transplant patients is still controversial because of the lack of prospective, large-scale clinical studies performed among diversely ethnic populations.