Stress response regulates cancer fibroblasts
- Resource Type
- Article
- Authors
- Faget, Douglas V.; Stewart, Sheila A.
- Source
- Nature Cell Biology; 20220101, Issue: Preprints p1-2, 2p
- Subject
- Language
- ISSN
- 14657392; 14764679
Fibroblasts become activated during wound repair and rapidly return to a ‘resting’ state, and are thus critical for normal tissue homeostasis and tumour development. A new study now reveals an important pro-tumorigenic role for the stress response in cancer-associated fibroblasts that may offer a new opportunity to limit tumour progression.