Wheat aphid, Sitobion avenae(Fab.), is a serious pest of wheat crop across the world. The present study was conducted to evaluate the potentials of the water plant extracts of Azadirachta indica(neem) or Eucalyptus camaldulensisand the entomopathogenic fungi (EPF); Beauveria bassianaor Metarhizium anisopliaeagainst the aphid species. After 5 days of applications, the combined mixture of B. bassianaand eucalyptus extract caused the maximum mortality rate (87%). While the combination of B. bassianawith neem extract showed the least rate (54%). Fecundity was negatively affected by the single and combined treatments of EPF and botanicals extracts. The lowest fecundity (7 nymphs per female) was recorded when the aphid was treated by the binary mixture of B. bassianaand eucalyptus extract. Correspondent maximum fecundity (29 nymphs per female) in 5 days was recorded in control treatment, while 23 nymphs were produced by a single female when treated with the binary mixture of B. bassianaand neem extract. The results indicated that EPF and botanical extracts (neem or eucalyptus) caused significant reduction in survival and fecundity of S. avenae.Therefore, they may be used as promising natural alternatives to synthetic insecticides against the wheat aphid species.