Continuous Hemofiltration in Hyperthermic Septic Shock Patients
- Resource Type
- Article
- Authors
- Pestaña, David; Casanova, Elena; Villagrán, María J.; Tormo, Carolina; Pérez-Chrzanowska, Hanna; Redondo, Javier; Caldera, María V.; Royo, Concepción
- Source
- The Journal of Trauma; October 2007, Vol. 63 Issue: 4 p751-756, 6p
- Subject
- Language
- ISSN
- 00225282
Severe hyperthermia commonly accompanies septic shock. High body temperature in absence of infection activates the inflammatory response and is associated with a high mortality. Three years ago, our hypothesis that sustained fever is harmful in septic shock led us to the development of a protocol aiming at decreasing hyperthermia (≥39.5°C) by means of hemofiltration when the patients did not respond to antipyretics. We present a report of temperature and hemodynamic changes and the outcome of 19 consecutive hyperthermic septic shock patients with multiorgan system failure and compare them with a historical similar group of patients in whom hyperthermia was not treated with hemofiltration.