The fall armyworm, Spodoptera frugiperda(J.E. Smith), is a destructive transboundary lepidopterous pest affecting more than 78 countries worldwide by infesting a wide array of agronomic and horticultural crops such as maize and cabbage. In a previous study, we demonstrated the synergized toxicity of three local plant extracts (Rhazya strictaDecne., Sophora mollis(Royle) Baker and Withania somnifera(L.) Dunal) with synthetic insecticide chlorantraniliprole against 3rd instar larvae of S. frugiperda. Here we evaluated the combined efficacy of indigenous entomopathogenic fungi (EPF) (Beauveria bassiana(Balsam) Vuillemin and Metarhizium anisopliae(Metschn.) Sorokin) along with above-mentioned plant extracts and chlorantraniliprole against 3rd instar larvae of S. frugiperdaunder laboratory and semi-field conditions. Toxicity bioassays with two EPF revealed that the highest concentration (1.0 × 109conidia per mL) of B. bassianacaused maximum larval mortality (76%) at 10th day post-treatment, followed by M. anisopliae, causing 70% larval mortality at the same concentration. In vitroevaluation of six binary combinations of LC33s of EPF (B. bassianaand M. anisopliae) and plant extracts revealed a synergized toxicity (83–87%) of four combinations comprising S. mollisand W. somniferawith B. bassianaand M. anisopliaeagainst 3rd instar S. frugiperdalarvae. Furthermore, these insecticidal combinations including chlorantraniliprole (@ half of the label-recommended dose) exhibited as well a significant synergized toxicity (i.e.37.75% at 1st day to 99.25% at 7th day post-treatment) under semi-field conditions, suggesting their further investigation under field against S. frugiperdaand on its natural enemies.