This article outlines the development of an embedded multidisciplinary, perinatal mental health clinic comprised of psychiatry, psychology, and social work. The perinatal period is a critical time for women's mental health and is associated with an increased risk of mood disorders. Thus, obstetrics and gynecology (Ob-Gyn) physicians encounter a variety of patient mental health needs. Integrated care within Ob-Gyn clinics has demonstrated improvements in depression, adherence, and overall treatment satisfaction.This article outlines the development of an embedded multidisciplinary perinatal mental health clinic comprised of psychiatry, psychology, and social work. Common patient and physician barriers are discussed. Guidelines for implementing an integrated model include educating medical staff and patients, implementing screening measures, and ongoing collaboration among providers. This article outlines the development of an embedded multidisciplinary, perinatal mental health clinic comprised of psychiatry, psychology, and social work. The perinatal period is a critical time for women's mental health and is associated with an increased risk of mood disorders. Thus, obstetrics and gynecology (Ob-Gyn) physicians encounter a variety of patient mental health needs. Integrated care within Ob-Gyn clinics has demonstrated improvements in depression, adherence, and overall treatment satisfaction.This article outlines the development of an embedded multidisciplinary perinatal mental health clinic comprised of psychiatry, psychology, and social work. Common patient and physician barriers are discussed. Guidelines for implementing an integrated model include educating medical staff and patients, implementing screening measures, and ongoing collaboration among providers. [[Psychiatr Ann. 2017;47(7):368–373.]