Discovery of TNG908: A Selective, Brain Penetrant, MTA-Cooperative PRMT5 Inhibitor That Is Synthetically Lethal with MTAP-Deleted Cancers.
- Resource Type
- Article
- Authors
- Cottrell, Kevin M.; Briggs, Kimberly J.; Whittington, Douglas A.; Jahic, Haris; Ali, Janid A.; Davis, Charles B.; Gong, Shanzhong; Gotur, Deepali; Gu, Lina; McCarren, Patrick; Tonini, Matthew R.; Tsai, Alice; Wilker, Erik W.; Yuan, Hongling; Zhang, Minjie; Zhang, Wenhai; Huang, Alan; Maxwell, John P.
- Source
- Journal of Medicinal Chemistry; 4/25/2024, Vol. 67 Issue 8, p6064-6080, 17p
- Subject
- Language
- ISSN
- 00222623