Supervillin binding to myosin II and synergism with anillin are required for cytokinesis
- Resource Type
- Article
- Authors
- Smith, Tara C.; Fridy, Peter C.; Li, Yinyin; Basil, Shruti; Arjun, Sneha; Friesen, Ryan M.; Leszyk, John; Chait, Brian T.; Rout, Michael P.; Luna, Elizabeth J.
- Source
- Molecular Biology of the Cell; December 2013, Vol. 24 Issue: 23 p3603-3619, 17p
- Subject
- Language
- ISSN
- 10591524; 19394586
Supervillin binding to myosin II is crucial for cytokinetic fidelity. This function complements that of anillin in promoting myosin II localization and cleavage furrow ingression during mammalian cell cytokinesis. Interactor analyses show that these proteins act through separate but overlapping pathways.