Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRASG12C with Demonstrable CNS Penetration.
- Resource Type
- Article
- Authors
- Kettle, Jason G.; Bagal, Sharan K.; Barratt, Derek; Bodnarchuk, Michael S.; Boyd, Scott; Braybrooke, Erin; Breed, Jason; Cassar, Doyle J.; Cosulich, Sabina; Davies, Michael; Davies, Nichola L.; Deng, Chao; Eatherton, Andrew; Evans, Laura; Feron, Lyman J.; Fillery, Shaun; Gleave, Emma S.; Goldberg, Frederick W.; Cortés González, Miguel A.; Guerot, Carine
- Source
- Journal of Medicinal Chemistry; 7/13/2023, Vol. 66 Issue 13, p9147-9160, 14p
- Subject
- Language
- ISSN
- 00222623