The article presents a comparative study on the efficacy of cognitive behavior therapy and supportive stress-management for the treatment of depression in patients who have undergone coronary artery bypass surgery at Washington University School of Medicine in St. Louis, Missouri. It reveals that cognitive behavior therapy has a higher percentage of remission of depression compared to stress-management, however, its covariate-adjusted Hamilton scores is lower. It mentions that cognitive therapy and stress-management are both effective in treating depression after coronary artery bypass surgery in terms of usual care. However, the former has greater and more durable effect and has several secondary psychological outcomes compared to supportive stress-management.