Histone Methyl Transferase G9a/GLP--A Novel Avenue in Pulmonary Arterial Hypertension Treatment?
- Resource Type
- Article
- Authors
- Veith, Christine; Knoepp, Fenja
- Source
- American Journal of Respiratory Cell & Molecular Biology; May2023, Vol. 68 Issue 5, p475-477, 3p
- Subject
- PULMONARY arterial hypertension
VASCULAR remodeling
ENDOTHELIN receptors
MOLECULAR biology
CYTOLOGY
EXTRACELLULAR matrix
- Language
- ISSN
- 10441549
The article presents the discussion on Pulmonary arterial hypertension (PAH) is a rare but serious disease. Topics include PAH being characterized by progressive pulmonary arterial remodeling, causing vessel lumen narrowing and elevated pulmonary arterial pressure; and alterations in the chromatin state of specific genes leading to the repression or activation.