This article presents an abstract of the research paper "Current Methods of Diagnosis and Treatment in Primary Cerebral Lymphoma Cases," which was discussed in the 13th Conference of the Polish Association of Neuropathologist. In this study, the diagnoses of 29 primary cerebral lymphoma were established from samples obtained from stereotactic biopsy or open surgery. Some of them were used for immediate diagnostics, others were a reserve for immunocytochemical responses and evaluation of proliferation activity and apoptosis. Diagnosis of ultra-small samples obtained from stereotactic biopsy in cerebral lymphoma cases allows to correct patients' treatment.