FURTHER STUDIES ON THE EFFECT OF ANTI- LYMPHOCYTIC ANTIBODY ON HUMORAL ANTIBODY FORMATION.
- Resource Type
- Article
- Authors
- James, K.; Pullar, Diane M.; James, Valerie S.
- Source
- Clinical & Experimental Immunology; Nov1968, Vol. 3 Issue 9, p963-972, 10p
- Subject
- IMMUNOGLOBULIN G
LYMPHOCYTES
SERUM albumin
ERYTHROCYTES
BLOOD cells
RATS
- Language
- ISSN
- 00099104
The article investigates the effect of anti-lymphocytic antibody on humoral antibody formation. More specifically, the effect of 3-, 6- and 12-day courses of anti-lymphocytic IgG treatment on the primary humoral response of random bred Wistar rats has been investigated. The primary response to alum precipitated bovine serum albumin was suppressed by all these courses. In contrast however the primary response to sheep erythrocytes was suppressed by the 6-day treatment alone or by a 3-day course augmented with azathioprine treatment.