Dosimetric analysis of 17 cardiac Sub-structures, Toxicity, and survival in ultra central lung tumor patients treated with SBRT.
- Resource Type
- Academic Journal
- Authors
- Ahmadsei M; Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.; Thaler K; Department of Cardiology, University Heart Center, University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Gasser E; Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.; Pouymayou B; Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.; Dal Bello R; Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.; Christ SM; Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.; Willmann J; Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.; Kovacs B; Department of Cardiology, University Heart Center, University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Balermpas P; Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.; Tanadini-Lang S; Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.; Saguner AM; Department of Cardiology, University Heart Center, University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Center for Translational and Experimental Cardiology (CTEC), Department of Cardiology, Zurich University Hospital, University of Zurich, 8952 Schlieren, Switzerland.; Mayinger M; Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.; Andratschke N; Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.; Guckenberger M; Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.
- Source
- Publisher: Elsevier Ireland Ltd. on behalf of European Society for Radiotherapy and Oncology Country of Publication: Ireland NLM ID: 101713416 Publication Model: eCollection Cited Medium: Internet ISSN: 2405-6308 (Electronic) Linking ISSN: 24056308 NLM ISO Abbreviation: Clin Transl Radiat Oncol Subsets: PubMed not MEDLINE
- Subject
- Language
- English
•Data on cardiac toxicity after SBRT for ultra-central lung tumors remains limited.•We analyzed the dose to 18 cardiac sub-structures and cardiovascular toxicity.•A SBRT regimen of 45 Gy in 8-10 fractions yields good local control and low toxicity.•The highest cardiac doses were observed in the pulmonary artery and left atrium.•Higher doses to the base of the heart seem to be associated with non-cancer deaths.
Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(© 2023 The Author(s).)