Chondrosarcoma secondary to hereditary multiple osteochondromas with spinal cord compression: A case report and systematic review.
- Resource Type
- Report
- Authors
- Silva JE; Department of Neurosurgery, Federal University of Ceará, Sobral, Ceará, Brazil.; Monteiro GA; Department of Neurosurgery, Federal University of Ceará, Sobral, Ceará, Brazil.; Silva STE; Department of Neurosurgery, Federal University of Ceará, Sobral, Ceará, Brazil.; Bezerra GMDS; Department of Neurosurgery, Federal University of Ceará, Sobral, Ceará, Brazil.; Cavalcante-Neto JF; Department of Neurosurgery, Federal University of Ceará, Sobral, Ceará, Brazil.; Bezerra DA; Department of Surgical Oncology, Federal University of Ceará, Sobral, Ceará, Brazil.; Department of Surgical Oncology, Santa Casa de Misericórdia's Hospital, Sobral, Ceará, Brazil.; Vasconcelos JLM; Department of Surgical Oncology, Santa Casa de Misericórdia's Hospital, Sobral, Ceará, Brazil.; Leal PRL; Department of Neurosurgery, Federal University of Ceará, Sobral, Ceará, Brazil.; Department of Neurosurgery, Santa Casa de Misericórdia's Hospital, Sobral, Ceará, Brazil.
- Source
- Publisher: Scientific Scholar LLC Country of Publication: United States NLM ID: 101535836 Publication Model: eCollection Cited Medium: Print ISSN: 2229-5097 (Print) Linking ISSN: 21527806 NLM ISO Abbreviation: Surg Neurol Int Subsets: PubMed not MEDLINE
- Subject
- Language
- English
- ISSN
- 2229-5097
Background: Hereditary multiple osteochondromas (HMOs) are a rare genetic disorder characterized by the formation of multiple benign osteochondromas that can undergo malignant transformation into chondrosarcoma.
Case Description: A 24-year-old male with a history of HMO and osteochondroma surgery 4 years ago, presented with back pain and paresthesias. The magnetic resonance showed a right paravertebral infiltrating mass at the T12-L1 level causing spinal cord compression. Following en bloc resection of the tumor, the patient's symptoms/ signs resolved. The final pathological diagnosis was consistent with a chondrosarcoma.
Conclusion: Chondrosarcomas secondary to HMO with spinal cord compression are rare. These patients often presenting with significant myelopathy/cord compression should undergo gross total resection where feasible to achieve the best outcomes.
Competing Interests: There are no conflicts of interest.
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