Frontal language areas do not emerge in the absence of temporal language areas: A case study of an individual born without a left temporal lobe.
- Resource Type
- Academic Journal
- Authors
- Tuckute G; Department of Brain and Cognitive Sciences and McGovern Institute for Brain Research, MIT, Cambridge, MA, 02139, USA. Electronic address: gretatu@mit.edu.; Paunov A; Department of Brain and Cognitive Sciences and McGovern Institute for Brain Research, MIT, Cambridge, MA, 02139, USA; Cognitive Neuroimaging Unit (UNICOG), NeuroSpin Center, 91191 Gif sur Yvette, France.; Kean H; Department of Brain and Cognitive Sciences and McGovern Institute for Brain Research, MIT, Cambridge, MA, 02139, USA.; Small H; Department of Brain and Cognitive Sciences and McGovern Institute for Brain Research, MIT, Cambridge, MA, 02139, USA; Department of Cognitive Science, Johns Hopkins University, Baltimore, 21218, MD, USA.; Mineroff Z; Department of Brain and Cognitive Sciences and McGovern Institute for Brain Research, MIT, Cambridge, MA, 02139, USA; Eberly Center for Teaching Excellence & Educational Innovation, CMU, Pittsburgh, PA, 15213, USA.; Blank I; Department of Brain and Cognitive Sciences and McGovern Institute for Brain Research, MIT, Cambridge, MA, 02139, USA; Department of Psychology, UCLA, Los Angeles, CA, 90095, USA.; Fedorenko E; Department of Brain and Cognitive Sciences and McGovern Institute for Brain Research, MIT, Cambridge, MA, 02139, USA; The Program in Speech and Hearing Bioscience and Technology, Harvard University, Boston, MA, 02114, USA. Electronic address: evelina9@mit.edu.
- Source
- Publisher: Pergamon Press Country of Publication: England NLM ID: 0020713 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3514 (Electronic) Linking ISSN: 00283932 NLM ISO Abbreviation: Neuropsychologia Subsets: MEDLINE
- Subject
- Language
- English
Language processing relies on a left-lateralized fronto-temporal brain network. How this network emerges ontogenetically remains debated. We asked whether frontal language areas emerge in the absence of temporal language areas through a 'deep-data' investigation of an individual (EG) born without her left temporal lobe. Using fMRI methods that have been validated to elicit reliable individual-level responses, we find that-as expected for early left-hemisphere damage-EG has a fully functional language network in her right hemisphere (comparable to the LH network in n = 145 controls) and intact linguistic abilities. However, we detect no response to language in EG's left frontal lobe (replicated across two sessions, 3 years apart). Another network-the multiple demand network-is robustly present in frontal lobes bilaterally, suggesting that EG's left frontal cortex can support non-linguistic cognition. The existence of temporal language areas therefore appears to be a prerequisite for the emergence of the frontal language areas.
(Copyright © 2022 Elsevier Ltd. All rights reserved.)