Semantic novelty modulates neural responses to visual change across the human brain.
- Resource Type
- Academic Journal
- Authors
- Nentwich M; Department of Biomedical Engineering, The City College of New York, New York, NY, USA. max.nentwich@gmail.com.; Leszczynski M; Departments of Psychiatry and Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA.; Translational Neuroscience Lab Division, Center for Biomedical Imaging and Neuromodulation, Nathan Kline Institute, Orangeburg, NY, USA.; Cognitive Science Department, Institute of Philosophy, Jagiellonian University, Kraków, Poland.; Russ BE; Translational Neuroscience Lab Division, Center for Biomedical Imaging and Neuromodulation, Nathan Kline Institute, Orangeburg, NY, USA.; Nash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine, New York, NY, USA.; Department of Psychiatry, New York University at Langone, New York, NY, USA.; Hirsch L; Department of Biomedical Engineering, The City College of New York, New York, NY, USA.; Markowitz N; The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA.; Sapru K; Department of Biomedical Engineering, The City College of New York, New York, NY, USA.; Schroeder CE; Departments of Psychiatry and Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA.; Translational Neuroscience Lab Division, Center for Biomedical Imaging and Neuromodulation, Nathan Kline Institute, Orangeburg, NY, USA.; Mehta AD; The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA.; Departments of Neurosurgery and Neurology, Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY, USA.; Bickel S; Translational Neuroscience Lab Division, Center for Biomedical Imaging and Neuromodulation, Nathan Kline Institute, Orangeburg, NY, USA.; The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA.; Departments of Neurosurgery and Neurology, Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY, USA.; Parra LC; Department of Biomedical Engineering, The City College of New York, New York, NY, USA. parra@ccny.cuny.edu.
- Source
- Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
- Subject
- Language
- English
Our continuous visual experience in daily life is dominated by change. Previous research has focused on visual change due to stimulus motion, eye movements or unfolding events, but not their combined impact across the brain, or their interactions with semantic novelty. We investigate the neural responses to these sources of novelty during film viewing. We analyzed intracranial recordings in humans across 6328 electrodes from 23 individuals. Responses associated with saccades and film cuts were dominant across the entire brain. Film cuts at semantic event boundaries were particularly effective in the temporal and medial temporal lobe. Saccades to visual targets with high visual novelty were also associated with strong neural responses. Specific locations in higher-order association areas showed selectivity to either high or low-novelty saccades. We conclude that neural activity associated with film cuts and eye movements is widespread across the brain and is modulated by semantic novelty.
(© 2023. The Author(s).)