Atypical Case of MOG Antibody-Associated Optic Neuritis with Roth Spots.
- Resource Type
- Academic Journal
- Authors
- Aboab J; Department of Internal Medecine, Centre Hospitalier National des Quinze-Vingts, Paris Cedex, France.; Errera MH; Department of Ophthalmology, UPMC Eye Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Espinoza S; Department of Neuroradiology, Centre Hospitalier National des Quinze- Vingts, Paris Cedex, France.; Girmens JF; CHNO des Quinze-Vingts, INSERM-DGOS CIC, Paris, France.; Héron E; Department of Internal Medecine, Centre Hospitalier National des Quinze-Vingts, Paris Cedex, France.
- Source
- Publisher: Informa Healthcare Country of Publication: England NLM ID: 9312169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-5078 (Electronic) Linking ISSN: 09273948 NLM ISO Abbreviation: Ocul Immunol Inflamm Subsets: MEDLINE
- Subject
- Language
- English
Purpose: To report an atypical case of MOG antibody-associated optic neuritis with Roth spots and widespread retinal hemorrhages.
Case Report: A 49-year-old woman complained of 1 week history painful visual loss in the left eye. Funduscopy exam showed a severe optic disc edema associated with multiple peripapillar hemorrhages, peripheral retinal hemorrhages and Roth spots in the left eye. Orbit MRI revealed an hyperintensity in the left optic nerve, enhanced with gadolinium. The serum Myelin Oligodendrocyte (MOG) antibodies was found positive. Early intravenous high dose of steroids rapidly improved visual acuity and fundus abnormalities rapidly resolved.
Conclusion: Retinal hemorrhages can also be detected in case of optic disc edema associated with an optic neuritis, as seen in MOGAD.