Anti-Ri-Associated Paraneoplastic Neurological Syndrome Revealing Breast Cancer: A Case Report.
- Resource Type
- Report
- Authors
- Tazi R; Neurology, Cheikh Khalifa Ibn Zayed Hospital, Faculty of Medicine, Mohamed VI University of Health Sciences (UM6SS), Casablanca, MAR.; Salimi Z; Neurology, Cheikh Khalifa Ibn Zayed Hospital, Faculty of Medicine, Mohamed VI University of Health Sciences (UM6SS), Casablanca, MAR.; Fadili H; Neurology, Cheikh Khalifa Ibn Zayed Hospital, Faculty of Medicine, Mohamed VI University of Health Sciences (UM6SS), Casablanca, MAR.; Aasfara J; Neurology, Cheikh Khalifa Ibn Zayed Hospital, Faculty of Medicine, Mohamed VI University of Health Sciences (UM6SS), Casablanca, MAR.; Hazim A; Neurology, Cheikh Khalifa Ibn Zayed Hospital, Faculty of Medicine, Mohamed VI University of Health Sciences (UM6SS), Casablanca, MAR.
- Source
- Publisher: Cureus, Inc Country of Publication: United States NLM ID: 101596737 Publication Model: eCollection Cited Medium: Print ISSN: 2168-8184 (Print) Linking ISSN: 21688184 NLM ISO Abbreviation: Cureus Subsets: PubMed not MEDLINE
- Subject
- Language
- English
- ISSN
- 2168-8184
Neurological paraneoplastic syndromes are a rare entity that affects patients with cancer. Anti-Ri antibodies affect the brain stem and produce a heterogeneous rapidly progressive subacute syndrome depending on the involvement of the different regions concerned. The most common clinical presentation is opsoclonus-myoclonus syndrome and paraneoplastic cerebellar degeneration. Here we report a case of a 60-year-old woman with a subacute static-kinetic cerebellar syndrome, cervical dystonia, and multiple cranial nerve palsies revealing a mammary adenocarcinoma. Anti-Ri antibodies were positive in her blood. Our observation underscored the importance of the identification of the tumor for early treatment management to avoid irreversible neurological manifestations.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2022, Tazi et al.)