Metronidazole‐induced encephalopathy after living donor liver transplantation.
- Resource Type
- Case Study
- Authors
- Takahashi, Kazuhiro; Tomidokoro, Yasushi; Oda, Tatsuya
- Source
- Transplant Infectious Disease. Feb2024, Vol. 26 Issue 1, p1-3. 3p.
- Subject
- *LIVER transplantation
*BRAIN diseases
*LIVER abscesses
- Language
- ISSN
- 1398-2273
This article discusses a case of metronidazole-induced encephalopathy in a 62-year-old Asian male who had undergone a liver transplant. The patient developed dysarthria and altered consciousness while being treated for a liver abscess. The diagnosis was made based on the patient's clinical history and imaging studies, which showed characteristic bilateral symmetric high signal intensity lesions in the cerebellar dentate nuclei and the inferior colliculi. Metronidazole-induced encephalopathy is a rare side effect of long-term metronidazole use and presents with dysarthria, cerebellar symptoms, and consciousness disturbance. Discontinuing the medication rapidly improved the patient's symptoms. The article emphasizes the importance of caution when prescribing metronidazole to liver transplant recipients with decreased liver function and immunocompetence. [Extracted from the article]