The developmental stage and tumour location of each lesion were indicated gl In this cohort, as shown in Figure 2A, an average of three multifocal lung nodules was sampled from each patient (range: 2-8). Seventy-two per cent of patients (23/32) had at least one invasive ADC nodule, and nine patients had preinvasive nodules only. GD tumours: genetically-different gl In this cohort, four patients were treated with chemotherapy, while 26 patients were treated with EGFR tyrosine kinase inhibitors (TKIs) including first-generation ( I n i = 15), second-generation (n = 2) and third-generation EGFR-TKIs ( I n i = 9). In patient 14, 15 of 25 mutations in the P14 T01 ADC tumour were also observed in the P14 T02 ADC tumour, which had 91 mutations. [Extracted from the article]