hsa-mir-210 Is a Marker of Tumor Hypoxia and a Prognostic Factor in Head and Neck Cancer.
- Resource Type
- Article
- Authors
- Gee, Harriet E.; Camps, Carme; Buffa, Francesca M.; Patiar, Shalini; Winter, Stuart C.; Betts, Guy; Homer, Jarrod; Corbridge, Rogan; Cox, Graham; West, Catharine M. L.; Ragoussis, Jiannis; Harris, Adrian L.
- Source
- Cancer (0008543X). 5/1/2010, Vol. 116 Issue 9, p2148-2158. 11p.
- Subject
- *CEREBRAL anoxia
*HEAD & neck cancer diagnosis
*CANCER prognosis
*RNA
- Language
- ISSN
- 0008-543X
The article presents a study which examines the role of three microRNAs as possible prognostic marker. The expression levels of each microRNAs were associated with clinicopathological variables and other hypoxia markers. The outcome shows that there were no correlation among the three microRNAs and clinicopathological variables. It concludes that the head and neck cancer's expression level of has-miR-210 associates with other methods for evaluating hypoxia and is correlated with prognosis.