SANE, a Novel LEM Domain Protein, Regulates Bone Morphogenetic Protein Signaling through Interaction with Smad1.
- Resource Type
- Article
- Authors
- Raju, G. Praveen; Dimova, Neviana; Klein, Peter S.; Hui-Chuan Huang
- Source
- Journal of Biological Chemistry. 1/3/2003, Vol. 278 Issue 1, p428. 10p. 1 Color Photograph, 8 Black and White Photographs, 1 Diagram, 1 Chart, 18 Graphs.
- Subject
- *PROTEINS
*BONE morphogenetic proteins
- Language
- ISSN
- 0021-9258
Identifies Smad1 antagonist effector (SANE), a novel protein with significant sequence similarity to nuclear envelop proteins. Mammalian model of bone formation; Inhibition of bone morphogenetic proteins; Interaction between SANE and Smad1; Nuclear translocation of Smad1.