MicroRNA-93 inhibits inflammatory cytokine production in LPS-stimulated murine macrophages by targeting IRAK4.
- Resource Type
- Article
- Authors
- Xu, Yan; Jin, Huiyi; Yang, Xiaolu; Wang, Lili; Su, Li; liu, Kun; Gu, Qing; Xu, Xun
- Source
- FEBS Letters. May2014, Vol. 588 Issue 9, p1692-1698. 7p.
- Subject
- *MICRORNA
*INFLAMMATION
*CYTOKINES
*NF-kappa B
*MACROPHAGES
*GENE targeting
*LABORATORY mice
- Language
- ISSN
- 0014-5793
Highlights: [•] miR-93 is downregulated in the eyes of LPS-induced EIU rats. [•] miR-93 is downregulated in LPS-treated RAW 264.7 cells. [•] miR-93 inhibits LPS-induced inflammatory cytokine production. [•] miR-93 inhibits LPS-induced activation of NF-κB signaling through IRAK4. [Copyright &y& Elsevier]