Screening assay for blood vessel maturation inhibitors.
- Resource Type
- Article
- Authors
- Fu, Chenglai; van der Zwan, Anita; Gerber, Stephanie; Van Den Berg, Susan; No, Elisa; C.H.Wang, Wayne; Sheibani, Nader; Carducci, Michael A.; Kachhap, Sushant; Hammers, Hans J.
- Source
- Biochemical & Biophysical Research Communications. Aug2013, Vol. 438 Issue 2, p364-369. 6p.
- Subject
- *BLOOD-vessel physiology
*DEVELOPMENTAL biology
*BIOLOGICAL assay
*IN vitro studies
*SCIENTIFIC observation
*HIGH throughput screening (Drug development)
*DATA acquisition systems
- Language
- ISSN
- 0006-291X
Highlights: [•] We model the complex process of blood vessel maturation in vitro. [•] Process can be observed in real-time. [•] Format allows for rapid and easy imaging/data acquisition. [•] System validated by drugs targeting and endothelial cells and pericytes. [•] Semi-high-throughput allows for drug screening. [ABSTRACT FROM AUTHOR]