Performance of the Xpert MTB/RIF Ultra Assay for Determining Cause of Death by TB in Tissue Samples Obtained by Minimally Invasive Autopsies To the Editor: An estimated 1.5 million deaths were attributable to TB in 2018.[1] However, some uncertainty exists as to the exact global figures, given that approximately 30% of incident cases are not diagnosed, and because of the difficulties of ascertaining TB as cause of death (CoD).[2] Undoubtedly, complete diagnostic autopsies (CDAs) constitute the gold standard for establishing a diagnosis of TB at death. In 31 patients, TB was the final CoD, 31 cases had TB disease at death but had died of another CoD, and in 18 cases DNA of M TB was detected but no histological lesions compatible with TB were found. [Extracted from the article]