TNF-alpha inhibitors in Systemic Lupus Erythematosus. A case report and a systematic literature review.
- Resource Type
- Article
- Authors
- Mosca, Marta; Tani, Chiara; Filice, Maria Elena; Carli, Linda; Delle Sedie, Andrea; Vagnani, Sabrina; Della Rossa, Alessandra; Baldini, Chiara; Bombardieri, Stefano
- Source
- Modern Rheumatology. Jul2015, Vol. 25 Issue 4, p642-645. 4p.
- Subject
- *SYSTEMIC lupus erythematosus
*SYNOVITIS
*JOINT diseases
*ARTHRITIS
*METHOTREXATE
- Language
- ISSN
- 1439-7595
Joint involvement is a common manifestation of systemic lupus erythematosus (SLE) and is described as a non-erosive mild synovitis. However some SLE patients may present a more severe joint involvement requiring aggressive therapy. We describe the case of a SLE patient with a severe arthritis unresponsive to methotrexate, successfully treated with anti-TNF-alpha drug as induction therapy and we report the results of a systematic literature review on the use of TNF-alpha inhibitors in SLE. [ABSTRACT FROM AUTHOR]