Central Role for G Protein--Coupled Phosphoinositide 3-Kinase Gamma in Inflammation.
- Resource Type
- Article
- Authors
- Hirsch, Emilio; Katanaev, Vladimir L.; Garlanda, Cecilia; Azzolino, Ornella; Pirola, Luciano; Silengo, Lorenzo; Sozzani, Silvano; Mantovani, Alberto; Altruda, Fiorella; Wymann, Matthias P.
- Source
- Science. 2/11/2000, Vol. 287 Issue 5455, p1049. 5p. 4 Graphs.
- Subject
- *PHOSPHOINOSITIDES
*LEUCOCYTOSIS
*PHYSIOLOGY
- Language
- ISSN
- 0036-8075
Presents information on a study on the roles of the receptor-activated isoforms of phosphoinositide 3-kinase (P13K) in leukocyte function. Assessment on the physiologic role of the P13K gamma isoform; Characterization of the migratory deficiencies observed; Conclusion.