ChemInform Abstract: Enantioselective Synthesis of Tertiary α-Hydroxy Phosphonates Catalyzed by Carbohydrate/Cinchona Alkaloid Thiourea Organocatalysts.
- Resource Type
- Article
- Authors
- Kong, Shasha; Fan, Weidong; Wu, Guiping; Miao, Zhiwei
- Source
- ChemInform. Jan2013, Vol. 44 Issue 5, pno-no. 1p.
- Subject
- Language
- ISSN
- 0931-7597
The cyanation of β-ketophosphonates with TmsCN in the presence of organocatalyst CCT and p-nitrophenol as additive affords α-trimethylsilyloxy-α-cyanophosphonates, which under acidic hydrolysis are quantitatively converted into the desired alcohols. [ABSTRACT FROM AUTHOR]