Tris(pentafluorophenyl)borane‐Catalyzed Oxygen Insertion Reaction of α‐Diazoesters (α‐Diazoamides) with Dimethyl Sulfoxide.
- Resource Type
- Article
- Authors
- Wu, Xiao‐Yang; Gao, Wen‐Xia; Zhou, Yun‐Bing; Liu, Miao‐Chang; Wu, Hua‐Yue
- Source
- Advanced Synthesis & Catalysis. Feb2022, Vol. 364 Issue 4, p750-754. 5p.
- Subject
- *DIMETHYL sulfoxide
*OXYGEN
*DIMETHYL sulfide
*AMIDES
- Language
- ISSN
- 1615-4150
A tris(pentafluorophenyl)borane‐catalyzed oxidation reaction of α‐diazoesters (α‐diazo amides) with dimethyl sulfoxide has been developed. The reaction proceeds under metal free conditions to afford a series α‐ketoesters and α‐ketoamides. The synthetic utility of this protocol is demonstrated through synthetic transformations and scaled‐up synthesis. [ABSTRACT FROM AUTHOR]