Finally, a structured and validated questionnaire for the assessment of symptoms in COVID-19 patients is highly desirable to characterize the full clinical spectrum of long COVID and improve the reliability and reproducibility of clinical studies. Keywords: chronic COVID syndrome; COVID-19; long COVID; long haulers; SARS-CoV-2 EN chronic COVID syndrome COVID-19 long COVID long haulers SARS-CoV-2 1685 1688 4 12/06/21 20211201 NES 211201 INTRODUCTION Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection can cause a wide array of symptoms ranging from mild to severe or fatal forms of coronavirus disease 2019 (COVID-19).1 Furthermore, it has been observed that in a proportion of patients a variable range of symptoms may persist for a long time.2 An increasing number of studies have been focused on long COVID, but they have mainly been concentrated on previously hospitalized severe COVID-19 patients reporting symptoms up to 6-months after illness.3,4 The main aim of this study was to evaluate the prevalence of COVID-related symptoms 12-months after the onset of mild-to-moderate disease. All patients completing the baseline interview were phoned from March 5, 2021 to March 22, 2021, so that all patients were re-contacted 12-months after the onset of symptoms; in case of a nonresponse, patients were re-contacted twice. [Extracted from the article]