Palladium-Catalyzed Medium-Ring Formation for Construction of the Core Structure of LaurenciaOxacycles: Synthetic Study of Laurendecumallene B.
- Resource Type
- Article
- Authors
- Yoshimitsu, Yuji; Inuki, Shinsuke; Oishi, Shinya; Fujii, Nobutaka; Ohno, Hiroaki
- Source
- Organic Letters. Vol. 15 Issue 12, p3046-3049. 4p.
- Subject
- *PALLADIUM catalysts
*RING formation (Chemistry)
*LAURENCIA
*CHEMICAL synthesis
*PROPARGYL alcohol
*CARBONATES
- Language
- ISSN
- 1523-7060
Palladium-catalyzed medium-ring formation from a cyclic propargyl carbonate via a ring-opening and -closing cascade proceeded at the central carbon atom of the propargyl unit to provide a tetrahydro-2H-oxocine derivative bearing the core structure of laurencia oxacycle. The synthetic application of this reaction to a possible laurendecumallene B precursor is also presented. [ABSTRACT FROM AUTHOR]