A Highly Efficient Synthesis Route for the Rapid Generation of 1,2,5,6-Tetrasubstituted Benzimidazoles.
- Resource Type
- Article
- Authors
- Duschmal�, J�rg J.; Woltering, Thomas J.; Bleicher, Konrad H.
- Source
- Synlett. 2008, Issue 10, p1467-1470. 4p.
- Subject
- *BENZIMIDAZOLES
*PALLADIUM
*NUCLEOPHILIC substitution reactions
*CHEMICAL synthesis
*NITROANILINE
- Language
- ISSN
- 0936-5214
Herein we describe the facile generation of novel benzimidazoles starting from 5-chloro-4-iodo-2-nitroaniline. A synthesis protocol was established which allows the parallel synthesis of compound arrays as well as the rapid generation of single representatives thereof. [ABSTRACT FROM AUTHOR]