Lipopolysaccharide can induce errors in anatomical measures of neuronal plasticity by increasing tracing efficacy.
- Resource Type
- Article
- Authors
- Weishaupt, Nina; Krajacic, Aleksandra; Fouad, Karim
- Source
- Neuroscience Letters. Nov2013, Vol. 556, p181-185. 5p.
- Subject
- *PHYSIOLOGICAL effects of lipopolysaccharides
*NEUROPLASTICITY
*DRUG efficacy
*DRUG administration
*NORMALIZATION (Sociology)
*GERMINATION
*AXONS
- Language
- ISSN
- 0304-3940
Highlights: [•] LPS administration can increase the number of traced corticospinal tract axons. [•] LPS-induced tracing differences can lead to artifacts when quantifying sprouting. [•] Normalization is required to avoid false-positive reports of axonal sprouting. [Copyright &y& Elsevier]