Expanded polyglutamine protein forms nuclear inclusions...
- Resource Type
- Article
- Authors
- Warrick, John M.; Paulson, Henry L.; Gray-Board, Gladys L.; Quang T. Bui; Fischbeck, Kenneth H.; Pittman, Randall N.; Bonini, Nancy M.
- Source
- Cell. 06/12/98, Vol. 93 Issue 6, p939. 11p. 5 Color Photographs, 1 Black and White Photograph, 1 Diagram, 1 Chart.
- Subject
- *PROTEINS
*INVERTEBRATES
*GLUTAMINE
*METABOLISM
- Language
- ISSN
- 0092-8674
Provides information on a study which demonstrates that cellular mechanisms of human glutamine-repeat disease are conserved in invertebrates. Directed expression of polyglutamine protein; How the expanded polyglutamine protein forms nuclear inclusions; Correlation of the formation of NI and cellular susceptibility.