Transition-metal-free regioselective and stereoselective C(sp2)–C(sp3) coupling of enamides with ethers or alkanes via photoredox-catalyzed cross-dehydrogenative coupling reactions.
- Resource Type
- Article
- Authors
- Tao, Ji-Yu; Wang, Ying-Xue; Zhang, Qing-Hong; Ni, Kun; Zhu, Tong-Hao; Zhao, Kai
- Source
- Green Chemistry. 5/21/2022, Vol. 24 Issue 10, p4004-4011. 8p.
- Subject
- *ALKANES
*ORGANIC dyes
*FUNCTIONAL groups
- Language
- ISSN
- 1463-9262
A generally applicable and robust regio- and stereoselective cross-dehydrogenative-coupling of enamides with ethers or alkanes via transition-metal-free photoredox-catalysis under environmentally benign and atom economic conditions is demonstrated. The visible-light-induced transformations proceed smoothly with the aid of non-expensive and non-poisonous organic dyes, forging geometrically defined and synthetically paramount β-alkylated enamides with broad substituent diversity and functional group compatibility. [ABSTRACT FROM AUTHOR]