Substrate‐Induced Synthesis of Coumarin‐Fused Quinolinones from Anilines, 4‐Hydroxycoumarins and DMSO under Air.
- Resource Type
- Article
- Authors
- Shi, Xu; Zhang, Qingqing; Wang, Anan; Jiang, Tao‐Shan
- Source
- Advanced Synthesis & Catalysis. 6/21/2022, Vol. 364 Issue 12, p2086-2090. 5p.
- Subject
- *QUINOLONE antibacterial agents
*ANILINE
*BIOCHEMICAL substrates
*CATALYSTS
- Language
- ISSN
- 1615-4150
Substrate‐induced synthesis of 6H‐Chromeno[4,3‐b]quinolin‐6‐ones has been developed directly from anilines, 4‐hydroxycoumarins and DMSO under air without any catalysts and additives in one pot. This protocol highlights dual roles of 4‐hydroxycoumarins which were not only used as reactants but also activated DMSO to provide one‐carbon unit in the desired products. [ABSTRACT FROM AUTHOR]