Trypanosome U-deletional RNA editing involves guide RNA-directed endonuclease cleavage, terminal...
- Resource Type
- Article
- Authors
- Cruz-Reyes, Jorge; Sollner-Webb, Barbara
- Source
- Proceedings of the National Academy of Sciences of the United States of America. 8/20/96, Vol. 93 Issue 17, p8901. 6p. 5 Black and White Photographs, 2 Diagrams.
- Subject
- *RNA editing
*TRYPANOSOMA brucei
- Language
- ISSN
- 0027-8424
Studies the mechanism of accurate in vitro RNA editing of Trypanosoma brucei ATPase subunit 6(A6) pre-mRNA. Deletion of the specified number of U residues; Endonuclease activity that cleaves the input pre-mRNA in a gRNA directed manner; Enzymatic activities cofractionate with the U-deletion activity.