Subendothelial retention of atherogenic lipoproteins in early atherosclerosis.
- Resource Type
- Article
- Authors
- Skalen, Kristina; Gustafsson, Maria; Rydberg, Ellen Knutsen; Hulten, Lilemor Mattson; Wiklund, Olov; Innerarity, Thomas L.; Boren, Jan
- Source
- Nature. 6/13/2002, Vol. 417 Issue 6890, p750. 5p. 3 Charts, 3 Graphs.
- Subject
- *LOW density lipoproteins
*APOLIPOPROTEINS
*ATHEROSCLEROSIS
*TRANSGENIC mice
- Language
- ISSN
- 0028-0836
Presents a study that examined the role of the subendothelial retention of atherogenic apolipoprotein B-containing low-density lipoproteins (LDL) in early atheroscelrosis in transgenic mice. Effect of an atherogenic diet on the aorta of transgenic mice; Analysis of the uptake and degradation of LDL; Examination of the ability of LDL to interact with biglycans.