Improving Oncology Trials Through Adaptive Designs.
- Resource Type
- Article
- Authors
- Reitsma, Dirk; Combest, Austin; Hummel, Jürgen; Simmons, Ashley
- Source
- Applied Clinical Trials. Apr/May2015, Vol. 24 Issue 4/5, p30-36. 7p.
- Subject
- *ONCOLOGY
*CANCER treatment
*BIOPHARMACEUTICS
*BIOMARKERS
*DRUG efficacy
- Language
- ISSN
- 1064-8542
The article offers information on the needed advances in oncology pipeline in cancer therapy. It mentions that the use of adaptive designs raised scientific and regulatory questions that slowed adoption by the biopharmaceutical industry. It also mentions that biomarkers are important in adaptive designs to provide early measures of efficacy.