Introduction: Negative symptoms (SN) may appear at the beginning of a first-episode psychosis (FEP) and seem to be associated with worse functional results, male gender, long duration of untreated psychosis (DUP), early age-at-oncet in FEP, neurocognitive disorders and traumatic life events. Objectives: Study the prevalence of NS in patients with drug-naive FEP. Describe the association between NS and gender, age-at-onset in FEP, DUP, premorbid functional level, positive and general psychopathology symptoms, depressive symptoms and childhood traumatic experiences. Methods: Cross-sectional study. Drug-naive FEP patients from Parc Sanitari Sant Joan de Déu were included. Sociodemographic variables, the Positive and Negative Syndrome Scale (PANSS), the Calgary Depression Scale for Schizophrenia (CDS), the Personal and Social Performance scale (PSP) and Childhood Trauma Questionnaire (CTQ) were administered. Following the Marder model we used the equation: Marder Negative = 5.8548 + (1.0209 * SANS score), to split the sample into NS group (Marder = 9) and non-NS group (Marder < 9). Results: A total of 155 patients (65,2% men and 34,8% women) were included. 58,6% of the patients met criteria for NS. PANSS Positive subscale was inversely associated with negative symptoms (p=0,04). Only gender, PANSS positive and general psychopathology subscales were found to be associated with negative symptoms using the regression analysis. Conclusions: The high prevalence of NS in our sample can be due to the low specificity of the used scales. We found an association between NS and PANSS positive subscale, PANSS general psychopathology subscale and gender. Further studies are needed to improve the conceptualization and evaluation of NS. [ABSTRACT FROM AUTHOR]