Authors' reply to Comment on antidotal use of lipid emulsion.
- Resource Type
- Letter
- Authors
- Mullins, Michael E.; Seger, Donna L.
- Source
- Clinical Toxicology (15563650). Dec2020, Vol. 58 Issue 12, p1357-1358. 2p.
- Subject
- *EMULSIONS
*LIPIDS
*INTRAVENOUS fat emulsions
- Language
- ISSN
- 1556-3650
Without serum drug concentrations, we have no way to differentiate a lethal overdose (where no treatment would improve outcome) from treatment failure. Use of lipid emulsion in the resuscitation of a patient with prolonged cardiovascular collapse after overdose of bupropion and lamotrigine. An assessment of the in-vivo effects of intravenous lipid emulsion on blood drug concentration and haemodynamics following oro-gastric amitriptyline overdose. [Extracted from the article]