Enteroinvasive Escherichia coli virulence-plasmid-carried apyrase (apy) and ospB genes are organized as a bicistronic operon and are subject to differential expression.
- Resource Type
- Article
- Authors
- Santapaola, Daniela; Casalino, Mariassunta; Petrucca, Andrea; Presutti, Carlo; Zagaglia, Carlo; Berlutti, Francesca; Colonna, Bianca; Nicoletti, Mauro
- Source
- Microbiology (13500872). Aug2002, Vol. 148 Issue 8, p2519-2529. 11p. 1 Diagram, 2 Charts, 11 Graphs.
- Subject
- *GENE expression
*MICROBIAL virulence
*PATHOGENIC bacteria
*SHIGELLA flexneri
*ESCHERICHIA coli
- Language
- ISSN
- 1350-0872
Shows that the expression of the virulence-plasmid-carried potential pathogenesis-associated apy gene is regulated by the same regulators that govern the expression of virulence genes in Shigella flexneri and enteroinvasive Escherichia coli. Determination of promoter activity in vivo; Transcription of ospB-apy operon; Primer-extension analysis of transcriptional start site.