This article, titled "Perianal extramammary Paget disease: our experience of two cases – a video vignette," discusses the cases of two patients, Patient A and Patient B, who both presented with symptoms of itching and redness in the perianal area. Both patients underwent a diagnostic process, including a specialized visit, clinical examination, colonoscopy, and MRI. A biopsy confirmed a diagnosis of extramammary Paget disease in both patients. The proposed intervention for treatment is the removal of the lesion with perianal reconstruction using a V-Y advancement flap. The article also provides details on the surgical procedure and the results for both patients. [Extracted from the article]