First synthesis of fully deprotected diimidotriphosphoric acid and derivatives designed for the...
- Resource Type
- Article
- Authors
- Saady, Mourad; Valleix, Alain
- Source
- Journal of Organic Chemistry. 6/16/95, Vol. 60 Issue 12, p3685. 7p. 15 Diagrams.
- Subject
- *PHOSPHORIC acid
*NUCLEOTIDES
*BIOSYNTHESIS
- Language
- ISSN
- 0022-3263
Describes the synthesis of fully deprotected diimidotriphosphoric acid. Derivation of PNPNP sequence from an all protected cyclic precursor; Removal of protective groups at the end of the synthesis; Developed procedure as a straightforward access to a class of nucleotide and dinucleotide analogs and other triphosphorylated compounds of biological interest.