Breadth and Dynamics of Human Norovirus-Specific Antibodies in the First Year of Life.
- Resource Type
- Article
- Authors
- Vielot, Nadja A; Brinkman, Amanda; DeMaso, Christina; Vilchez, Samuel; Lindesmith, Lisa C; Bucardo, Filemon; Reyes, Yaoska; Baric, Ralph S; Ryan, Elizabeth P; Braun, Ralph; Becker-Dreps, Sylvia
- Source
- Journal of the Pediatric Infectious Diseases Society. Oct2022, Vol. 11 Issue 10, p463-466. 4p.
- Subject
- *BINDING sites
*RICE
*TIME
*BLOOD collection
*IMMUNOASSAY
*DIETARY supplements
*NOROVIRUS diseases
*RNA viruses
*VIRAL antibodies
*CHILDREN
- Language
- ISSN
- 2048-7193
We measured antibody binding to diverse norovirus virus-like particles over 12 months in 16 children. All had maternal antibodies at 2 months, with estimated lowest levels at 5 months of age. Antibody increases after 3 months suggested natural infections. This information could guide the timing of future norovirus vaccines. [ABSTRACT FROM AUTHOR]